The impact of climate change on numerous ecological processes, such as the interactions between microbes and plants, has become a major global concern. The health of the entire plant community, the cycling of nutrients, and the operation of ecosystems depend on these relationships. The dynamics and distribution of these interactions can shift in response to changes in the climate. Wide-ranging effects on ecosystem functions result from these changes in plant-microbe dynamics brought on by climate change. Plant productivity and nutrient acquisition are affected by changes in symbiotic connections, including mycorrhizal associations and nitrogen-fixing partnerships, which are a result of climate change. Threats to plant health and agricultural output might arise from pathogenic interactions that intensify in response to shifting environmental circumstances. Determining future changes in ecosystem dynamics and developing practical plans for sustainable agriculture and ecosystem management require a thorough examination of how climate change affects interactions between plants and microbes. Forecasting how ecosystems will react to climate change and creating plans to lessen its negative effects on plant health and the ecosystem depend on having a thorough understanding of the precise mechanisms underlying the changes in plant-microbe interactions brought about by climate change. The present review explores the complex interplay between plant-microbe interaction dynamics and climate change, providing insight into the processes via which changing weather patterns influence these relationships.