Aiming at the effectiveness evaluation of Manned/Unmanned Aerial Vehicles(M/UAVs) cooperative air-to-ground attacking, the classic ADC model is selected as the evaluation method. The expression of capability matrix \(\boldsymbol{C}\) is reconstructed based on the real test data. On this basis, the efficiency calculation of four collaborative schemes is completed. Finally, the \(\boldsymbol{T}\) distribution hypothesis test method is selected to complete the efficiency set evaluation of different schemes, and the influencing factors of the results are analyzed. The results show that, among the four schemes, the system efficiency of scheme 2 is higher, and the increase of the number of aircraft will not improve the overall system efficiency indefinitely. The evaluation method can be applied to evaluate and compare the system efficiency of different cooperative schemes of M/UAVs, and can provide theoretical reference for the evaluation and operational use of M/UAVs cooperative.