Disability studies have been influencing various academic and practical disciplines for decades. However, its influence on design has yet to create a significant impact in both design education and practice. Furthermore, the socio-cultural aspects of disability are typically still at the margins of the discipline, albeit with clear and significant ramifications on both theory and praxis. In this article, we wish to present a practice-based approach towards highlighting a necessary aspect of design for disability, focusing on its socio-cultural implications. We start by highlighting the importance of disability studies to the social venues of design, including its unique approach. We base our claims on design education and outcomes by BA and MA/M.Des students. These in-depth descriptions portray two distinctive non-Western cultures (India and Israel), in which the socio-cultural aspects of these design projects lead to innovative conclusions. Implementing these conclusions will benefit design theoreticians, educators and practitioners alike.