The chapter by Dawn Apgar PhD, LSW, ACSW, and Mackaully Parada, MSW, LCSW, focuses on Social Work: A Profession Aimed at Helping to Realize Vatican II’s Call to Action. The chapter is inspired by the innovative double major in social work and Catholic studies at Seton Hall University. The authors, who are social work faculty, reflect on the Second Vatican Council social teachings and especially on Pope John XXIII’s call for the Catholic Church to connect with 20th-century people in an increasingly secularized world. Central to this calling was the firm belief that the Church’s practices needed to be improved and its teaching needed to be presented in a way that would be relevant and understandable. The social work profession, which has a long history of assisting those in poverty who are marginalized and oppressed, has fought hard for professional status, but has had difficulty with establishing a strong professional identity and status. Interestingly, the profession is rooted in the same values, such as integrity, dignity and worth of the individual, service, importance of human relationships, and social justice, and many of the same approaches that are the basis of Catholic Social Teaching. This chapter identifies how Catholic-based institutions can make better use of their social work courses and programs and conversely how social work courses and programs can integrate Catholic Social Teaching more fully, helping to realize Vatican II’s call. Many students want opportunities to put their faith into action. Social work, as a professional practice profession, provides a path to do so. This chapter explicitly identifies ways in which Catholic Social Teaching and social work can strengthen their linkage.