Plastic and bioremediation are a rapidly emerging subject of study with numerous potential applications. The demand for more environmentally friendly and sustainable solutions to the problem of plastic waste motivates research on this subject. Further research should focus on developing more effective and economical cost strategies for bioremediation and plastic recycling. Furthermore, research must focus on developing innovative methods and strategies to reduce plastic waste at its origin. Additional study is required to improve comprehension of the environmental and health consequences of plastic and bioremediation. Recent advancements in plastic recycling include the development of microbial enzymatic degradation methods that break down plastics into their basic monomers, including bacteria, fungi, and microalgae capable of degrading various plastic polymers. Advancements in biodegradable plastics are increasing, providing alternatives that can naturally dissolve without causing environmental harm. Enhanced plastic recycling techniques can yield substantial economic advantages by minimizing raw material expenses and diminishing dependence on fossil fuels for plastic manufacturing. This review includes biodegradable plastics and microorganisms that facilitate the degradation of manufactured and natural plastics. Furthermore, the application of metagenomic and bioengineering methodologies for plastic bioremediation. In addition, the application of genetic engineering, bioinformatics, and synthetic biology to improve plastic bioremediation. Ultimately, upcoming prospects and challenges encompass competition, regulation, and escalating costs, with emerging technologies to address these issues.