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In the growing field of cancer-associated biomedical applications, core-shell nanostructures have proven to be a paradigm shift, presenting improved accuracy and effectiveness in the treatment and screening domain. Here we have a summary of the diverse functions of these nanoparticles (NPs) throughout various cancer treatment techniques, which include combinational therapies that combine numerous treatments in a synergistic manner, chemotherapy, photothermal, photodynamic, gene therapy, and sonodynamic therapies. Core-shell nanoparticles dramatically boost the degree of sensitivity and selectivity of imaging tests like magnetic resonance imaging (MRI), positron emission tomography (PET) scans, and SPECTs in diagnostic evaluations, rendering tumor identification more precise and timely. The section emphasizes the need for further research centered on multimodal platforms, biocompatibility, targeted accuracy, and clinical translation while focusing on the future possibilities of these components in enhancing cancer treatment and diagnostics. These developments might usher in an era of innovation in cancer therapeutics by offering the prospect of more efficient, precise, and customized cancer treatments and diagnostic tools.

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Core-Shell Nanoconstructs for Cancer-Based Biomedical Applications

  • 章节

  • 发表日期：

    2025年

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  • Anoushka Mukharya,
  • Rahul Pokale,
  • Amrita Arup Roy,
  • Viola Colaco,
  • Gaurisha Alias Resha Ramnath Naik,
  • Srinivas Mutalik,
  • Namdev Dhas,
  • Ritu Kudarha

摘要

In the growing field of cancer-associated biomedical applications, core-shell nanostructures have proven to be a paradigm shift, presenting improved accuracy and effectiveness in the treatment and screening domain. Here we have a summary of the diverse functions of these nanoparticles (NPs) throughout various cancer treatment techniques, which include combinational therapies that combine numerous treatments in a synergistic manner, chemotherapy, photothermal, photodynamic, gene therapy, and sonodynamic therapies. Core-shell nanoparticles dramatically boost the degree of sensitivity and selectivity of imaging tests like magnetic resonance imaging (MRI), positron emission tomography (PET) scans, and SPECTs in diagnostic evaluations, rendering tumor identification more precise and timely. The section emphasizes the need for further research centered on multimodal platforms, biocompatibility, targeted accuracy, and clinical translation while focusing on the future possibilities of these components in enhancing cancer treatment and diagnostics. These developments might usher in an era of innovation in cancer therapeutics by offering the prospect of more efficient, precise, and customized cancer treatments and diagnostic tools.