H oilfield belongs to complex fault block oilfield, with many types of reservoirs and poor physical properties. Fracturing is an important means to transform and increase reserves and production of such reservoirs. At present, the proportion of fracturing wells in H Oilfield is high, the fracturing effect of different types of reservoirs is uneven, the effect is decreasing year by year, and the difficulty of well selection and layer selection is increasing year by year. The original qualitative fracturing well selection and layer selection standard is no longer applicable to the current development situation. Instead, it is urgent to establish new criteria for well and layer selection aiming at increasing production. Based on the statistical analysis of the effects of 215 fracturing wells implemented in this block in the past seven years, the influencing factors of fracturing effect are clarified from the aspects of geology, development and technology. It is determined that 8 parameters, such as single well controlled reserves, fracturing thickness, number of layers of ≥ 2 m, permeability, daily oil production before fracturing, well cluster injection-production ratio, sand-adding strength, and liquid addition have a great influence on the fracturing effect. The corresponding weights of various parameters in ultra-low permeability sandstone reservoirs, tuffaceous sandstone reservoirs and conglomerate reservoirs are determined by grey correlation method. The standard reconstruction and scientific quantification of well selection and layer selection for different types of reservoirs are realized. The example proves that the quantitative standard is reasonable and effective. In the well formation selected by this method, the initial daily oil increase of a single well was 3.0t and the annual oil increase was 386t after the fracturing was implemented, achieving low well efficiency. This technique provides basis and guidance for screening potential wells in H Oilfield.