Shale is widely distributed in the Shuangyi section of the Luxiang Fault Depression, which has good oil and gas properties and engineering quality. Through the deployment of old well testing and risk exploration wells, it is believed that it has exploitable benefits. However, the degree of well control in the Danan Depression located in the Luxiang Fault Depression is low, and the distribution of well points is uneven, which affects the accuracy of structural mapping. In addition, research has shown that the fractures in the study area are relatively developed, and multiple fractures show oil films. Therefore, it is urgent to explore a set of fracture prediction techniques to guide the selection and optimization of horizontal well trajectories. Aiming at the accuracy of construction mapping and the characteristics of tracture distribution.The velocity mapping method controlled by structural change points in the design trajectory of horizontal wells is used to reduce inclination and velocity errors.Additionally,the most suitable multi-attribute integrated fracture prediction technology for this research area has been tested and selected,establishing the development zones of fracture planes and longitudinal concentrated sections. Through the comprehensive application of the above technical methods, a horizontal well was successfully deployed with a 100% drilling rate of the target zone. The results of this research are also of significant guiding importance for the implementation and trajectory optimization of horizontal well schemes in similar geological situations in the future.