The infrared UAV target tracking method based on detection information guidance can provide real-time target location information for other anti-UAV detection systems, and provide support for solving the problems of UAV interference, black flight and encroachment on others’ territory. In this paper, the imaging distortion parameters of the infrared camera are corrected first. Then, according to the detection information, the deviation between the target position and the image center is calculated, and it is linearly converted into the deflection of the head. Finally, according to the current Angle and deflection of the head, the azimuth and pitch Angle of the head are adjusted to track the target. The experimental results show that the average transverse and longitudinal deviations between the target position and the image center in the four tracking experiments are 26.13 pixels and 25.01 pixels respectively.