Acid fracturing was an effective technique for increasing oil well productivity. The production capacity of some wells in the BC zone of Baobab oilfield has decreased, and it was necessary to conduct relevant researches to explore the feasibility of acid fracturing in the reservoir. Using the rocks in the BC zone of Baobab oilfield as the research object, the properties of rock were analyzed through XRD, SEM and thin section analysis. The dissolution experiments were conducted to select the highly efficient acids. The rock cores were artificially split to simulate fractures, and the conductivity and etching morphology of rock fractures by different acids were studied through three-dimensional laser scanning and conductivity testing. The results indicated that the minerals of rock in the BC zone were mainly plagioclase, kalifeldspar, and quartz, with small amounts of calcite, magnetite, biotite, chlorite, and illite. The dissolution rate of mud acid, polyhydrogen chelating acid, and fluoroboric acid was relatively high the etching morphology roughness of the fracture surface was strong by the polyhydrogen chelating acid, which had a positive impact on the conductivity. The non-uniformity of the etching morphology of mud acid and fluoroboric acid was relatively low. The conductivity of the polyhydrogen chelating acid after etching fracture was higher than that of the mud acid and fluoroboric acid, and it still could maintain a higher conductivity under high closure stress. This study confirmed the feasibility of using acid fracturing to increase production in the granite reservoir of Baobab oilfield, providing ideas for the similar reservoir stimulation.