Plastic pollution and its impact on the terrestrial and marine ecosystems is a major concern globally, and the situation was exacerbated after the outbreak of COVID-19 and usage of single-use plastics. Millions of plastic items of different sizes, being discharged daily, worldwide, causing Plastic pollution. This situation was exacerbated, during the COVID-19 pandemic, as millions of people are using single-use plastic face mask, gloves and face shields as personal protective equipment (PPE). The continuous and massive increase of gloves, masks and some sorts of wrapping made from single-use plastics, would end up littering land and marine environments ecosystems globally, a visible side-effect of the increased use of PPE, causing hazards. Moreover, such pollution would lead to emissions of greenhouse gases, potentially harming environment. This briefing delivers a synopsis of the environmental and climate impacts of single-use gloves and masks used for COVID-19 protection from June to August 2020. To the best of our knowledge, this study presents the first such information from the Middle East. It pinpoints the need for further knowledge and action, such as a safe, sustainable, transparent and unconventional waste management processes related to COVID-19 in order to reduce the negative impacts now and in any future events. It identifies the need for further knowledge and action to reduce these impacts now and in any future events.