With the increasing number of space targets, the earth’s orbital environment has become increasingly complex. Aiming at the potential safety hazards caused by non-cooperative targets approaching the space station, this paper proposes a collaborative planning control method based on cluster nano satellites to intercept non-cooperative target. Firstly, the interception mission is analyzed, and the autonomous allocation of the interception points, interception time constraint, fuel consumption constraint, formation configuration constraint and the maneuvering capability of nano satellites are comprehensively considered. Furthermore, the fitness function considering multiple constraints is constructed, and the mathematical model of the interception path planning is established. Finally, aiming at the time constraint given by the interception mission, an interception path planning algorithm for collaborative networking of multiple nano satellites based on inner and outer nested optimization is proposed. The simulation results show that the proposed algorithm can achieve successful interception of non-cooperative target in a fixed time.