The increasing need for sustainable construction and infrastructure has driven the innovative incorporation of waste materials to mitigate environmental impact and improve resource efficiency. Utilizing waste products such as sawdust and glass powder in concrete mixtures not only addresses waste disposal challenges, but also has the potential to enhance concrete properties, contributing to more sustainable building practices. This research paper examines the potential of using waste sawdust ash and glass powder as partial replacements for fine aggregates in concrete mixture. Both normal concrete and innovative concrete mixtures (which incorporated 0.6% sawdust and varied amounts of 5% and 9% glass powder as partial replacements for fine aggregates) were cast into concrete cylinders with dimensions of 150 and 300 mm and tested for compressive strength. Additionally, a numerical study using the Response 2000 software was conducted to evaluate the flexural performance of 400 × 155 × 3500 mm reinforced concrete beams incorporating these innovative concrete mixtures. The results show that incorporating 0.6% sawdust and 9% glass powder increased the compressive strength by 40% compared to the normal concrete. Furthermore, the numerically derived flexural capacities of reinforced concrete beams containing these materials were comparable to the control beam.