The cinchona industry had connected Priangan to the world when colonialism was at its peak. Bandung became the epicenter of the world's cinchona, known as the cinchona capital. Priangan supplies more than 90 percent of the world's cinchona needs. This study aimed to reveal the destruction of Priangan cinchona production in global dynamics and find a way out through a cultural perspective. The method used is descriptive qualitative, with historical, archeological, and anthropological approaches, and used Social Engineering Concept from James C. Scott. The destruction of cinchona production is not only an economic problem but also a cultural problem. Traces of cinchona culture are now largely lost, so important historical evidence of cinchona's past glory is also lost. From a cultural perspective, the development of cinchona can still be developed considering that the downstream industry is still producing regularly. The cinchona waste produced can be used to develop the creative economy. The garden workers who have lived for generations in the plantation environment still survive. Loyalty is valued for maintaining the previous generation's legacy, which is practiced in everyday life. Plantation societies that are increasingly besieged by global penetration are able to survive.