Cold Bituminous Mix (CBM) is an environmentally and economically advantageous alternative to traditional Hot Bituminous Mix, despite its inferior mechanical properties such as low early life strength, lengthy curing periods, and coating issues. The study aims to investigate factors such as the effect of the combination of non-conventional fillers and curing time on the fatigue behaviour of CBM. To address the issues related to CBM, MoRTH gradation of DBM grade II is used for the mix preparation. Other physical properties of aggregate and emulsion tests were done as per the Bureau of Indian Standards to check the quality of the materials used in the mix and were well within limits. Analysis of the microstructure of filler using Fourier transform infrared spectroscopy and X-ray fluorescence results revealed the chemical composition of fillers, Combination of filler that was finalised were Combination 1 (MF 25%, AF 15%, FA 60%) and Combination 2 (MF 15%, AF 15%, FA 30%, RHA 40%). Mix preparation with modified filler combinations of non-traditional fillers and nominal mix, for a different curing period of (4, 7, 14, and 28-day effect) at 40 °C with 3 trials each for the different sets of tests to be done on fatigue performance. Performing indirect tensile tests and repeated load tests on the cylindrical specimen prepared on a Superpave gyratory compactor with dimensions of 100 mm diameter and 63.5 mm height and mix preparation as per IRC SP 100 (2014). Mix showed higher fatigue resistance with an increase in curing effect for modified mix with approximately 185% in comparison with nominal mix, where approximately 170% increase in fatigue life, and with approximately 29% increase due to the effect of fillers.