Clinical Review of Ocular Tumors and Phakomatosis
摘要
Intraocular tumors are categorized based on a variety of factors, including malignant potential, incidence, age of presentation, anatomical location within the eye, tissue origin, relationship to systemic disease, and whether they are primary ocular tumors or secondary deposits from distant cancers. Uveal melanoma (UM) is the most frequent primary intraocular malignancy in adults, with the choroid being the most commonly involved site. In adults, the most prevalent secondary intraocular malignancies are metastatic breast cancer in females and metastatic lung cancer in males. In children, retinoblastoma (RB) is the most common primary intraocular malignancy in children, while secondary intraocular malignancies often result from leukemia, mostly affecting the uveal tract.