Polyether ether ketone (PEEK) stands out as a high-temperature engineering polymer widely utilized in medical applications due to its exceptional mechanical attribute’s, chemical durability and hot strength. Fused deposition modeling (FDM) 3D printing offers a cost-effective and versatile manufacturing method with high material efficiency. This study aims to produce flawless PEEK samples via 3D printing, enhancing their mechanical properties to match those of injection molded parts. Tensile samples were printed in horizontal, vertical, and 45° inclined orientations under optimized process conditions. All orientations shared consistent printing conditions. The evaluation focused on deformability, print quality, and tensile properties. Results revealed that horizontally printed samples exhibited superior tensile strength and elongation compared to vertically or 45° inclined prints. Notably, a remarkable ultimate tensile strength of 76.7 MPa was attained in the horizontal build direction. This was achieved with specific parameters: nozzle temperature at 405 °C, Printing bed temperature of 180 °C, 0.1 mm of print thickness and printing speed set at 5 mm/s.