While West Bengal experienced moderate seismic activity with five earthquakes exceeding magnitude 3.0 in the past year, its location on the Zones III-IV boundary with an average zone factor of 0.16 g warrants cautious planning, particularly for high-rise projects on the outskirts of Kolkata. The primary concern from a geotechnical point of view for the subsoil stratigraphy in the outskirts of Kolkata region is the presence of loose, cohesionless soil beneath these new constructions which makes them susceptible to liquefaction even during moderate earthquakes. Therefore, determining site-specific seismic parameters becomes crucial for geotechnical engineers to assess potential liquefaction risks. This study proposes a unique approach utilizing sophisticated in-situ test like SDMT to precisely measure shear wave velocities and compressibility characteristics of the Kolkata subsoil. These geotechnical parameters are incorporated in the DEEPSOIL software to generate site-specific seismic responses for various earthquake scenarios (Mw = 6.9 and 7.5). The study reveals that the site-specific peak ground acceleration (PGA) values are quite alarming when compared with previous research works. The resulting spectral acceleration (Sa/g) values at surface level are compared with the response spectrum specified in IS 1893 (Part 1): 2016 for medium soil. The study concludes that this combined approach of advanced in-situ testing and DEEPSOIL analysis simplifies the process of conducting site-specific seismic response analysis, allowing for more informed and safer design decisions for high-rise buildings.