The rapid evolution of technology has been pivotal in reshaping industries, and the supply chain sector is no exception. As companies strive to remain competitive, innovation emerges as a critical driver of adaptation and transformation. This chapter aims to explore the profound impact of disruptive technologies (DTs) on supply chain management (SCM), specifically focusing on technologies such as the Internet of Things (IoT), blockchain, artificial intelligence (AI), and data science. In doing so, the chapter aims to provide a comprehensive overview of the historical development of DTs, analyze their current applications in enhancing the efficiency and efficacy of supply chain activities, and outline strategies for leveraging these technologies to gain a competitive advantage. The chapter employs a thorough review of existing literature and case studies to examine the integration of DTs in smart supply chains. Our review reveals that DTs have significantly improved the monitoring, creation, and transportation of commodities, fostering a more autonomous and cognitive-aware supply chain. Additionally, the chapter highlights the dual role of DTs in driving corporate digital transformation and enhancing overall performance. By dissecting the benefits and challenges associated with implementing DTs, this chapter contributes to the body of knowledge on smart supply chain management, offering valuable insights for practitioners and researchers aiming to harness the full potential of technological advancements in this field.