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The pathogenesis of OMG is closely related to antibody mediation, and the detection of serum antibodies is an important means of diagnosing OMG. Relevant antibodies include: acetylcholine receptor antibody (AChR-Ab), muscle-specific tyrosine kinase antibody (MuSK-Ab), and low-density lipoprotein receptor-related protein 4 antibody (LRP4-Ab), etc. OMG with both AChR-Ab and MuSK-Ab negative is called double seronegative OMG (dSN-OMG).

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Serological Test for Ocular Myasthenia Gravis

  • 章节

  • 发表日期：

    2025年

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  • Qing Zhou,
  • Jian Chen

摘要

The pathogenesis of OMG is closely related to antibody mediation, and the detection of serum antibodies is an important means of diagnosing OMG. Relevant antibodies include: acetylcholine receptor antibody (AChR-Ab), muscle-specific tyrosine kinase antibody (MuSK-Ab), and low-density lipoprotein receptor-related protein 4 antibody (LRP4-Ab), etc. OMG with both AChR-Ab and MuSK-Ab negative is called double seronegative OMG (dSN-OMG).