Magnetic resonance imagingMagnetic Resonance Imaging (MRI) (MRI) and fluorescence molecular tomographyFluorescence Molecular Tomography (FMT) (FMT) is a hybrid imaging technique that combines MRI and FMT to visualize and characterize molecular and cellular processes in vivo, using both targeted and untargeted fluorescent agents along with magnetic resonance signal. This chapter explains the key role of hybrid MRI-FMT imaging in field of molecular imaging and medicine. The key factors such as components, advantages, disadvantages, and application of hybrid MRI–FMT imaging systems were described. The major advantages are precise imaging of location and nature of disease such as tumour, atherosclerosis, myocardial infarction, neuro disorders, etc., and disadvantages include operating cost, MRI, and FMT signal interference. Advancements in imaging technology and molecular probes are enhancing MRI-coupled FMT's capabilities, aiming to translate it from preclinical research to clinical applications for disease diagnosis and monitoring.

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Magnetic Resonance Imaging/Fluorescence Molecular Tomography Hybrid Imaging: Advantages, Limitations, and Applications

  • Ramalingam Shenbhagaraman,
  • Sudarson Jenefar

摘要

Magnetic resonance imagingMagnetic Resonance Imaging (MRI) (MRI) and fluorescence molecular tomographyFluorescence Molecular Tomography (FMT) (FMT) is a hybrid imaging technique that combines MRI and FMT to visualize and characterize molecular and cellular processes in vivo, using both targeted and untargeted fluorescent agents along with magnetic resonance signal. This chapter explains the key role of hybrid MRI-FMT imaging in field of molecular imaging and medicine. The key factors such as components, advantages, disadvantages, and application of hybrid MRI–FMT imaging systems were described. The major advantages are precise imaging of location and nature of disease such as tumour, atherosclerosis, myocardial infarction, neuro disorders, etc., and disadvantages include operating cost, MRI, and FMT signal interference. Advancements in imaging technology and molecular probes are enhancing MRI-coupled FMT's capabilities, aiming to translate it from preclinical research to clinical applications for disease diagnosis and monitoring.