Women’s role in the quest for freedom and equality has neither been widely acknowledged nor received more profound research attention than that of the menfolk in African liberation historiography. Indeed, their authoritative status in many African societies’ political, economic, and socio-cultural spheres is not disputable but somewhat shrouded in controversy. In colonial Nigeria, women in many places and instances, like their counterparts in other parts of the colonised states, realised that they had to struggle for rights that men had taken for granted. During this period, women's anger was focused on the policies and activities of the colonial government, missionaries, foreign trading companies and their agents like local chiefs or native authorities. This paper argues, in contrast to the pre-colonial experience, that colonialism in Nigeria ushered in specific economic and socio-political changes that brought about inequality in education, taxation and gender relations, which affected women in their search for freedom and equality.