This article proposes the Mixed Resonance Pair (MRP) as a method for efficient transmission of oscillatory signals between different brain regions to enhance overall cognitive function and coordination. Through simulation analysis in a seven-layer excitatory-inhibitory (E-I) neural network, it reveals the impact of feedback connections on interregional information transmission in the brain. The results indicate that feedback connections to excitatory clusters significantly enhance the network’s ability to transmit neural information, while feedback connections to inhibitory clusters suppress sustained oscillations, maintaining system stability. By adjusting feedback connection parameters, the network’s transmission capability can be significantly improved. Furthermore, the network shows a preference for transmitting periodic oscillatory signals based on the overall loop delay, suggesting that different delays have varying effects on the transmission capability of different frequency oscillatory signals. In essence, MRP connections can regulate the dynamic pathway selection of oscillatory information of different frequencies.