The automation of EPC project cost contributes to the efficiency and accuracy of related projects, and has high benefits for social needs and overall economic development. As a common computer algorithm, neural network algorithm is widely used in various fields. The automation and intelligence of neural network algorithm can improve the efficiency and accuracy of EPC project cost control. Traditional cost control methods often require a lot of manual operation and management, and are prone to errors and loopholes. Neural network algorithm can improve the efficiency and accuracy of data utilization through automatic data entry and analysis, integrated management, automatic calculation and statistics, so as to achieve the final realization of the project and provide theoretical basis and relevant data basis for related research.