Nitrogen-doped graphene has shown promise as an exceptionally adaptable platform for creating hybrid materials that combine superior electrical, chemical, and structural properties for advanced technological applications. This chapter presents a comprehensive discussion of the synthesis, structural characteristics, and functional behaviours of N-G integrated with metals, non-metals, and other material systems. The integration of N-G with metallic species, including transition and noble metals, enhances catalytic activity and charge transfer efficiency through metal–nitrogen coordination, which is particularly beneficial for electrocatalytic reactions such as the oxygen reduction and hydrogen evolution processes. Similarly, incorporation with non-metallic dopants and compounds, such as boron, sulfur, and phosphorus, provides improved chemical stability, flexibility, and multifunctionality suitable for sensors, membranes, and energy storage systems. Beyond these, the chapter examines the integration of N-G with diverse materials such as MXenes, metal–organic and covalent–organic frameworks, quantum dots, carbon nanotubes, polymers, and oxides, where synergistic interactions yield materials with hierarchical porosity, high conductivity, and tunable surface chemistry. Various synthesis approaches, including pyrolysis, hydrothermal and solvothermal reactions, chemical vapor deposition, and self-assembly, are reviewed alongside advanced characterization techniques like XRD, TEM, XPS, BET, and electrochemical analyses that reveal the structure–property correlations governing performance. The chapter concludes with comparative insights into different N-G hybrid systems, outlining challenges such as interface control, material stability, and scalable fabrication, while highlighting future directions in AI guided materials design, green synthesis, and cross disciplinary collaboration for next generation functional nanocomposites.