This chapter provides a comprehensive examination of how climate change influences plant-parasitic nematodes (PPNs), focusing on the expansion of geographical distribution, breakdown of nematode resistance, host defense mechanisms, nematode abundance in soil, and increase in the number of generations. Climate change may expand the geographical range of PPNs due to warmer temperatures, though impacts vary by species and region. It could weaken plant resistance to PPNs, affecting crop health. Climate change alters plant defense mechanisms, potentially making plants more vulnerable to PPNs. Studies indicate that PPN abundance in soil might increase with higher CO2 levels, though results vary depending on temperature and precipitation changes. Warmer temperatures could lead to more PPN generations per year, impacting agricultural systems, though extreme heat might reduce reproduction in some species. Recent studies highlight the complexity of these interactions, aiming to inform agricultural strategies under changing climatic conditions.