This chapter provides a comprehensive analysis of the international sanctions imposed on Russia since 2022 and the country’s subsequent counter-sanctions and economic adaptation strategies. It examines the multifaceted nature of the sanctions, which targeted the financial sector, high-tech imports, and key commodity exports, with the stated aim of compelling a change in state behavior. The study employs a detailed review of macroeconomic data, trade statistics, and policy measures to assess the profound impact on the Russian economy. The findings reveal a trajectory of unexpected economic resilience. Contrary to the objective of inducing collapse, the Russian economy demonstrated adaptive capacity, achieving positive GDP growth, a surge in manufacturing, and a robust labor market. This resilience was underpinned by robust fiscal stimulus, stringent capital controls, and a historic strategic reorientation of foreign trade away from Europe and towards Asia, with China emerging as the dominant partner. This pivot is intrinsically linked to a broader geopolitical realignment, reinvigorating the BRICS bloc as a platform for de-dollarized trade and alternative financial infrastructure. The authors conclude that while the sanctions have imposed significant long-term costs, exposed technological vulnerabilities, and constrained access to global capital and advanced technology, they have failed to achieve their maximalist objectives. The principal outcome has been the accelerated fragmentation of the global economy, marking a decisive shift away from the paradigm of interdependence towards a new era of contested multilateralism and economic blocs centered on strategic autonomy and non-Western integration.