The digital revolution has fundamentally altered international relations by establishing new domains of power that extend beyond traditional geographic boundaries. This chapter analyzes how small states, defined as those with populations under 10 million, and middle powers, with populations between 10 and 100 million and regional influence, maintain sovereignty in cyberspace despite the dominance of larger technological powers. Comparative analysis of national strategies demonstrates that these states actively shape their cyber futures. Four principal strategies are identified: niche specialization, diplomatic innovation, regional cooperation, and strategic balancing. The findings indicate that resource constraints foster innovation, as limited resources promote specialization, smaller bureaucracies enable rapid adaptation, and necessity drives creative solutions. Estonia converted cyber vulnerability into global leadership; Singapore established itself as a regional cybersecurity hub; Israel utilized military expertise for economic benefit; and Turkey engages in strategic balancing between technological ecosystems. These examples illustrate that knowledge can surpass material resources in cyberspace, creating opportunities for asymmetric influence. As cyberspace becomes central to economic prosperity and national security, understanding these strategies offers valuable models for nations seeking cyber sovereignty through calibrated connectivity rather than digital self-sufficiency.