High-Entropy Alloys (HEAs) are the latest concept in materials engineering that basically alter the conventional approach to alloy design. As an emerging area with huge potential for application-oriented research and progress in technology, HEAs frequently consist of five or more major components combined in almost equal quantities. Because of their wide compositional range and significant mixing entropy, these alloys perform better mechanically than standard engineering alloys. To increase the use of HEAs in manufacturing and production, where they are joined in similar or dissimilar manner by welding, it is important to select the best welding procedures with optimized parameters. Because the microstructure and properties of weldments vary widely according to the material system, welding technique, and process conditions, thus careful understanding of HEA weldments is fundamental for the suitable applications. Fusion-based welding process, diffusion bonding (DB), explosive welding (EW), and solid-state welding (SSW) process have demonstrated usefulness for better mechanical performance of HEA weld joints. The use of interlayers of HEA has resulted in suppressing the formation of intermetallic phases and maximizing the joint mechanical properties. The scope of this chapter is to examine the current challenges, advancements, and future outlook of HEA joining, with a focus on microstructural evolution, phase formation, and mechanical properties of HEA weldments.