Wind turbines are generally located in micro terrain areas with high altitude and high humidity, and wind turbine blades are prone to icing in winter. At present, the icing of wind turbine blades is one of the important problems facing wind power generation, which can lead to a decrease in wind turbine power generation efficiency, blade fatigue damage, and even shutdown accidents. In response to the shortcomings of existing mechanical and chemical de-icing methods, this paper proposes an intelligent electric de-icing equipment based on graphene and metal mesh integrated heating and lightning protection. By optimizing the arrangement of heating elements, designing temperature control strategies and protection systems for different zones, and combining artificial climate chamber experiments and numerical simulations, the ice melting effect and reliability of the equipment were verified. The results show that the equipment can achieve 10 mins of ice melting at a power density of 1300W/m2 in an environment of −5 °C, and the insulation performance remains stable after 100 cycles of testing. The research results provide a new efficient and environmentally friendly solution for wind turbine blade de-icing technology.