Scholarlink

The gut microbiota is a large group of microorganisms that reside within the host organism, influencing significant pathways and mechanisms by altering specific compounds such as short-chain fatty acids in bile acid metabolism. The result is quite astonishing that these microscopic creatures impact human health not only in gastrointestinal problems but also in neuropsychiatric illnesses. The gut microbiota acts equally as the human brain in a certain percentage, and they mimic the human genome as the gut microbiome. The therapeutic potential of certain drugs and the pharmacological activity of certain foods and nutritional products, interestingly, depend upon the gut microbiota composition. This chapter discusses the gut-brain axis and neurological disorders. We tried to establish the link between gut microbiota and the bile acid metabolism that might regulate the neuropsychiatric disorders.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Microbiota-Gut-Brain Axis and Its Potential Implications on Neuropsychiatric Disorders with a Special Emphasis on Bile Acid Signaling

  • 章节

  • 发表日期：

    2026年

查看全文
  • Muhasina K M,
  • Puja Ghosh,
  • Deepika N P,
  • Krishnaveni Nagappan,
  • Dhanabal S. Palaniswamy,
  • Md Ekhtiar Uddin,
  • Md Abul Hassan

摘要

The gut microbiota is a large group of microorganisms that reside within the host organism, influencing significant pathways and mechanisms by altering specific compounds such as short-chain fatty acids in bile acid metabolism. The result is quite astonishing that these microscopic creatures impact human health not only in gastrointestinal problems but also in neuropsychiatric illnesses. The gut microbiota acts equally as the human brain in a certain percentage, and they mimic the human genome as the gut microbiome. The therapeutic potential of certain drugs and the pharmacological activity of certain foods and nutritional products, interestingly, depend upon the gut microbiota composition. This chapter discusses the gut-brain axis and neurological disorders. We tried to establish the link between gut microbiota and the bile acid metabolism that might regulate the neuropsychiatric disorders.