Glycan-related research information is an essential element in glycoscience. So far, a lot of information has been organized as databases, but they are distributed, and the data formats and descriptions vary, which is a challenge. Therefore, researchers have to use multiple databases, each with different usage methods, requiring a lot of effort. However, with the development of the glycoscience portal GlyCosmos [1], the glycan structure repository GlyTouCan [2] and the mass spectrometry data storage GlycoPOST [3] have been organized, and the management of glycan data is gradually becoming easier. In addition, database integration in Japan, Europe, and the United States is progressing, and the organization of the GlySpace Alliance [4] is forming a trend of integration both domestically and internationally. Semantic web technologies (RDF, OWL, SPARQL) are being used to support this integration, and basic research such as the development of glycan-related ontologies that make this possible is also progressing.

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Challenges and Technological Development in the Integration of Glycan-Related Information

  • Issaku Yamada

摘要

Glycan-related research information is an essential element in glycoscience. So far, a lot of information has been organized as databases, but they are distributed, and the data formats and descriptions vary, which is a challenge. Therefore, researchers have to use multiple databases, each with different usage methods, requiring a lot of effort. However, with the development of the glycoscience portal GlyCosmos [1], the glycan structure repository GlyTouCan [2] and the mass spectrometry data storage GlycoPOST [3] have been organized, and the management of glycan data is gradually becoming easier. In addition, database integration in Japan, Europe, and the United States is progressing, and the organization of the GlySpace Alliance [4] is forming a trend of integration both domestically and internationally. Semantic web technologies (RDF, OWL, SPARQL) are being used to support this integration, and basic research such as the development of glycan-related ontologies that make this possible is also progressing.