Optical Coherence Tomography (OCT) is a light-based, 3D imaging technique used in ophthalmology for eye disease detection. Every so often, the OCT device requires re-calibration, where setup parameters are re-evaluated to create updated correction vectors. These are critical for OCT imaging as they enable the removal of signal nonlinearities that lead to image resolution degradation. Here, we demonstrate that a nonlinear raw OCT signal can be efficiently corrected, i.e., linearised, using a neural network, without a priori knowledge of OCT device parameters. We test several training strategies for their successful performance - signal pre-processing and training dataset size variation - on both the computer-generated and experimental data.

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Training Strategies for Nonlinearity Removal from Optical Coherence Tomography Signals

  • Krzysztof A. Maliszewski,
  • Magdalena A. Urbańska,
  • Varvara Vetrova,
  • Sylwia M. Kolenderska

摘要

Optical Coherence Tomography (OCT) is a light-based, 3D imaging technique used in ophthalmology for eye disease detection. Every so often, the OCT device requires re-calibration, where setup parameters are re-evaluated to create updated correction vectors. These are critical for OCT imaging as they enable the removal of signal nonlinearities that lead to image resolution degradation. Here, we demonstrate that a nonlinear raw OCT signal can be efficiently corrected, i.e., linearised, using a neural network, without a priori knowledge of OCT device parameters. We test several training strategies for their successful performance - signal pre-processing and training dataset size variation - on both the computer-generated and experimental data.