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Taurine, a sulfur-containing amino acid abundant in various foods, exhibits significant potential in alleviating diet-induced lipid metabolism disorders. This chapter highlights taurine’s therapeutic effects on hepatic steatosis, hypertriglyceridemia, and hypercholesterolemia induced by high-fat, high-sucrose, and high-cholesterol diets, respectively. Taurine modulates key metabolic pathways, including AMPK activation, suppression of lipogenic genes, and enhancement of cholesterol catabolism. Additionally, taurine influences gut microbiota composition and short-chain fatty acid production, further improving lipid homeostasis. This work underscores taurine’s role as a dietary corrective agent, advocating for its integration into strategies combating metabolic syndrome through personalized nutrition.

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Taurine: A Food-Derived Compound Alleviates Diet-Induced Lipid Metabolism Disorder

  • 章节

  • 发表日期：

    2026年

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  • Qi Song,
  • Hiroaki Oda

摘要

Taurine, a sulfur-containing amino acid abundant in various foods, exhibits significant potential in alleviating diet-induced lipid metabolism disorders. This chapter highlights taurine’s therapeutic effects on hepatic steatosis, hypertriglyceridemia, and hypercholesterolemia induced by high-fat, high-sucrose, and high-cholesterol diets, respectively. Taurine modulates key metabolic pathways, including AMPK activation, suppression of lipogenic genes, and enhancement of cholesterol catabolism. Additionally, taurine influences gut microbiota composition and short-chain fatty acid production, further improving lipid homeostasis. This work underscores taurine’s role as a dietary corrective agent, advocating for its integration into strategies combating metabolic syndrome through personalized nutrition.