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Biological components can change in a synergistic and antagonistic way in response to biotic and abiotic stresses and during synthesis and metabolomics. Thus, a technique is needed to simultaneously determine the distribution and concentration of several targeted biological components, such as amino acids, nucleotides, and other biomolecules. A relatively new technology, imaging mass spectrometry (IMS), enables the direct mapping and imaging of biomolecules on tissue sections. IMS permits simultaneous detection of multiple analytes on a single section of sample tissue, even in the absence of target-specific markers such as antibodies.

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Recent Advances in Imaging Mass Spectrometry

  • 章节

  • 发表日期：

    2026年

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  • Shu Taira,
  • Hitomi Shikano,
  • Masahiro Takano,
  • Kenichi Takano,
  • Nobuyuki Takahashi,
  • Takashi Sekiguchi

摘要

Biological components can change in a synergistic and antagonistic way in response to biotic and abiotic stresses and during synthesis and metabolomics. Thus, a technique is needed to simultaneously determine the distribution and concentration of several targeted biological components, such as amino acids, nucleotides, and other biomolecules. A relatively new technology, imaging mass spectrometry (IMS), enables the direct mapping and imaging of biomolecules on tissue sections. IMS permits simultaneous detection of multiple analytes on a single section of sample tissue, even in the absence of target-specific markers such as antibodies.