Evaluating growth and development is crucial to understanding the health status of adolescents. This assessment, through physical examination, requires healthcare experts and can be challenging due to subjectivity and privacy concerns. Similarly, psychosocial growth is subjective and also requires complex evaluations by professionals. This complexity makes physical growth assessment based on anthropometric measures a more useful and convenient indicator for monitoring growth. Therefore, anthropometric measurements should be assessed with more precise methods and calibrated equipment. Considerations of precision, reliability, and validity are essential for growth assessments when planning health strategies, nutritional status, and overall well-being. The study design should be carefully selected based on the objectives. An adequate sample size is also critical in capturing the true variability of the study population. Adolescents undergo a growth spurt due to prepuberty and puberty; thus, the development of growth centile charts necessitates appropriate assessment methodology and validations to effectively evaluate growth status and capture its variations. The differences, velocity, and acceleration charts are essential in creating reference growth centiles for a population, especially for adolescents. The appropriate statistical methodology, based on exploratory data analysis and modeling for estimating centiles, has fundamental implications. GAMLSS is a more flexible model that can capture the growth spurt due to puberty in adolescents, utilizing various distribution families, smoothing functions, and the ability to model each parameter with multiple covariates. Cross-validation enhances confidence in the generalizability of the statistical model and growth centiles for the target population. These growth centile charts are vital for early detection of growth disorders, nutritional assessments, monitoring, and informed decision-making in clinical and public health contexts.