Small Bowel and Colonic Motility Test, Colonic Transit Time Testing
摘要
Colonic transit time (CTT) measurement is an objective method to evaluate colonic motility. The most useful indication of CTT is chronic constipation, particularly in cases that do not respond well to initial treatments typically provided in primary care. Chronic constipationChronic constipation is commonly categorized into slow transit constipation, normal transit constipation, and defecatory disorders by CTT. CTT measurement is a necessary test for classifying chronic constipationChronic constipation by pathophysiology and selecting appropriate treatment methods. There are several methods for measuring CTT. The radiopaque markerRadiopaque marker method involves orally ingesting a capsule containing radiopaque markersRadiopaque marker coated with barium, followed by tracking the markers with plain abdominal X-rays. This is the simplest and most cost-effective method for measuring CTT. The radioisotope (RI)Radioisotope (RI) method involves ingesting a test meal mixed with an RI-labeled compound, followed by counting the radiation activity in the colon over time using a gamma camera to measure CTT. Internationally, CTT measurement using wireless capsulesWireless capsule is also performed. In Japan, measuring CTT tests are not yet performed in daily clinical practice. The widespread use of these tests in daily clinical practice in Japan is strongly desired in the future.