There are many diseases that must be differentiated from chest pain, including so-called “killer diseases” such as myocardial infarction and aortic dissection. We observed a 58-year-old man who visited our hospital complaining of chest pain. Electrocardiography, chest CT, coronary angiography with acetylcholine provocation testing, and upper gastrointestinal endoscopy showed no abnormalities, and he was diagnosed with non-cardiac chest pain (NCCP) due to GERD. A potassium-competitive acid blocker (P-CAB) was administered, and the frequency of chest pain decreased. GERD is the most common cause of NCCP, with esophageal motility disorders being less frequent.

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Case Discussion, Chest Pain

  • Masahiko Inamori

摘要

There are many diseases that must be differentiated from chest pain, including so-called “killer diseases” such as myocardial infarction and aortic dissection. We observed a 58-year-old man who visited our hospital complaining of chest pain. Electrocardiography, chest CT, coronary angiography with acetylcholine provocation testing, and upper gastrointestinal endoscopy showed no abnormalities, and he was diagnosed with non-cardiac chest pain (NCCP) due to GERD. A potassium-competitive acid blocker (P-CAB) was administered, and the frequency of chest pain decreased. GERD is the most common cause of NCCP, with esophageal motility disorders being less frequent.