Constructed wetlands are engineered systems designed and built to simulate biological processes for wastewater treatment and pollutant removal, within a semi-controlled natural environment. In this chapter, we present a detailed techno-economic analysis of various types of constructed wetlands, including free water surface, subsurface flow and hybrid systems. Primary design parameters such as hydraulic loading rate, hydraulic retention time, substrate, plant species selection and pollutant removal efficiency have been discussed with respect to technical assessment. Economic parameters, including capital cost, operation and maintenance requirements and strategies for cost reduction, are also evaluated for the determination of system feasibility in diverse contexts. The case studies presented here demonstrate successful implementation throughout the world, reiterating that constructed wetlands as adaptable and efficient technology compared to natural wetlands for wastewater treatment, being particularly suitable for areas that seek sustainable and cost-effective environmental solutions.