This chapter has examined the vital role of contracts and boundaries in shaping ethical, effective supervision within interprofessional education and collaborative practice. By grounding supervision in clear agreements, mutual accountability, and respect for diverse professional roles, supervisors help foster a culture of trust and shared responsibility. Drawing on the WHO Framework, we explored how institutional readiness, curriculum design, faculty development, and competency-based learning outcomes interconnect to support collaborative practice. Real-world scenarios illustrated both effective and ineffective approaches to boundary management, highlighting the importance of clear role definition, open dialogue, and reflective practice. The chapter highlights the need to adapt contracts and boundaries to evolving contexts, including hybrid and digital supervision models, while emphasizing cultural competence and ethical leadership. Finally, we presented practical tools, such as checklists, decision guides, and supervision frameworks, to help supervisors confidently navigate complex dynamics. By integrating these strategies, educators and clinicians can cultivate supervision relationships that are transparent, equitable, and responsive, ultimately enhancing professional development and improving patient care across disciplines. As healthcare systems grow more complex, these foundational practices will remain essential to preparing a collaborative, competent workforce.