Polyvinylidene fluoride, or PVDF, is a semicrystalline piezopolymer that has garnered significant attention due to its exceptional piezoelectric and pyroelectric properties, particularly in its β-phase. Furthermore, PVDF has significant mechanical rigidity, endurance, and chemical resistance. PVDF is an environmentally friendly polymer material and an excellent substitute for lead-based piezoceramics (PZTs) due to its lead-free composition, suitable for biomedical, structural, acoustic, and wearable sensor applications. PVDF can be fabricated into thin films or nanofibers according to specifications utilizing various facile fabrication techniques such as electrospinning, 3D printing, solution coating, and solution casting etc. Recent breakthroughs in co-polymerization and nanocomposite creation significantly boost the sensitivity of PVDF, its crystalline phase purity, and facilitate its seamless incorporation into next-generation improvements for piezo and pyroelectric device applications. This book chapter examines the physical, piezoelectric, and pyroelectric characteristics of PVDF material, its fabrication process, the adaptability of PVDF-based sensors, and the future roadmap towards the potential development route of high-performance piezoelectric and pyroelectric sensors.