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Radiotherapy (RT) for benign diseases remains a complex therapeutic option, requiring a careful balance between clinical benefit and the potential risk of radiation-induced cancer (RIC). Although its utilization has declined in many regions due to historical safety concerns, modern radiotherapy techniques and updated evidence-based protocols have redefined its role, particularly for patients with conditions unresponsive to standard therapies. This chapter provides a comprehensive overview of current clinical indications, advances in RT technology, and evolving risk assessment strategies. It integrates epidemiological findings, phantom-based modeling, and ethical considerations to guide appropriate patient selection and clinical decision-making. International practice patterns and emerging data support the renewed relevance of RT in the select benign conditions.

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Introduction of Radiation Therapy for Benign Diseases

  • 章节

  • 发表日期：

    2026年

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  • Kanika Sood Sharma

摘要

Radiotherapy (RT) for benign diseases remains a complex therapeutic option, requiring a careful balance between clinical benefit and the potential risk of radiation-induced cancer (RIC). Although its utilization has declined in many regions due to historical safety concerns, modern radiotherapy techniques and updated evidence-based protocols have redefined its role, particularly for patients with conditions unresponsive to standard therapies. This chapter provides a comprehensive overview of current clinical indications, advances in RT technology, and evolving risk assessment strategies. It integrates epidemiological findings, phantom-based modeling, and ethical considerations to guide appropriate patient selection and clinical decision-making. International practice patterns and emerging data support the renewed relevance of RT in the select benign conditions.