In situ gellable hydrogels have gained attention as an effective therapeutic success over the challenges generated in wounds and their associated complications due to their transitional property from liquid to a gel state upon application. These hydrogels can be easily applied in a fluid form, adapting to the contours of uneven wound surfaces, and then solidify in response to physiological triggers such as changes in pH, temperature, or ion concentration. The gel formation at the wound site maintains a moist environment, supports oxygen permeability, and serves as a barrier against infections, thereby enhancing tissue repair. Additionally, these hydrogels can be designed to enable the delivery of therapeutic biomolecules involving growth factors, antimicrobials, and stem cells in a controlled way, induce the formation of a vascular network, and stimulate collagen synthesis. Their properties of biocompatibility, biodegradability, and adjustable mechanical strength make these in situ gellable hydrogels suitable for healing of both superficial as well as deep and irregular wounds. Overall, in situ geling hydrogels offer a flexible and promising platform for advanced wound care therapies.