Aiming at the potential leakage and corrosion risks caused by CO2 in the CCUS technology of oilfields, this paper develops a CCUS corrosion control technology to ensure the safe production of CCUS. Firstly, a prediction model for the steady-state flow of CO2 injection is established by combining with the characteristics of the oil reservoirs in the Liaohe Oilfield. Secondly, through corrosion simulation experiments, the determination of the corrosion rate and the analysis of the main controlling factors are carried out. Finally, according to the wellbore structure of the injection-production wells, the anti-corrosion process is determined for the key risk nodes, and field experiments are carried out. Based on the model, the simulation of the CO2 parameters in the wellbore of Well X-36-62 in the Liaohe Oilfield is completed, and the parameters such as the partial pressure of CO2 and the phase state under different working conditions are determined. Through the analysis of the results of laboratory tests, the temperature, the partial pressure of CO2 and the salinity are the main controlling factors for corrosion. By analyzing the risk nodes according to the wellbore structure, the anti-corrosion technology of the annulus protection fluid is formed and field tests are carried out. It is measured that the corrosion rate is much lower than the oilfield standard of 0.076 mm/a, which proves that there is almost no corrosion under this method. This paper innovatively uses the node analysis method to analyze the corrosion influencing factors and risk nodes in the application process of CCUS, and proposes an anti-corrosion process countermeasure for CCUS development and conducts field tests, providing a technical basis for further expanding the application and low-cost development of CCUS.