As climate disasters intensify across the Asia–Pacific region in 2024, with record-breaking heatwaves, floods, and rising sea levels threatening millions, this chapter examines transformative gender-responsive approaches that are fundamentally reshaping climate adaptation and disaster risk reduction. The study focused on three distinct geographic contexts within the Asia–Pacific region: coastal Bangladesh, the Solomon Islands, and central Vietnam. These locations were strategically selected to represent diverse ecological, socio-economic, and cultural contexts within the broader region while sharing significant vulnerability to climate impacts. Through rigorous analysis of existing case studies, policy frameworks, and regional assessments, the research reveals how women-led initiatives are bridging critical gaps between traditional ecological wisdom and modern climate science, creating more resilient and inclusive communities. The study introduces a conceptual framework that examines three interconnected dimensions: gender-sensitive early warning systems, inclusive resource governance, and transformative institutional approaches. Findings demonstrate that gender-responsive climate action not only enhances community resilience but also addresses deep-rooted social inequities. This work contributes to the broader discourse on effective climate adaptation in the Global South, where the intersection of gender and climate crisis demands immediate attention.