The accelerating emergence of a networked society, driven by hyper-connectivity among organizations, individuals, and intelligent systems, has reinforced the importance of collaboration among autonomous entities. Collaborative Networks have evolved into diverse forms, including Collaborative Business Ecosystems (CBEs), which now appear in multiple sectors. In parallel, sustainability has become a critical global concern, calling for coordinated action across disciplines. This paper explores the intersection of collaboration and sustainability, focusing on CBEs through two complementary lenses: an exogenous perspective on their contribution to sustainable development, and an endogenous perspective on sustaining collaboration within the ecosystem. The discussion is supported by literature insights and examples from research conducted at the CTS Research Center.