Triplet-of-triplet spectral patterns—three narrow, high-density frequency bands separated by two silent gaps—emerged consistently in isolated protein molecules and in living systems but vanished in non-living or unconscious states. Zooming into each primary band reveals a secondary triplet structure whose peak distributions shift with conformational changes, reflecting underlying biomolecular dynamics. We detected these kHz, MHz, and GHz ultra-high-frequency signatures non-invasively on human skin, plant seed junctions, leaves animal tissues, and cultured cells; they were absent in living cells, varied with GCS levels in coma patients and sleep states but not in propofol induced anesthesia (where megahertz rectangular bursts instead dominate), and abolished postmortem. Seeds and root junctions with stem of a plant resembles GCS 3.0 of a human subject under coma. Triplet of triplet is a marker of consciousness not a triplet alone, also, different peaks of triplet band in MHz has significant implications in conscious state, one can distinguish which part of spinal cord or brain MHz signal is coming from, simply by looking at the pattern. Together, these findings establish the triplet-of-triplet around 6–26 MHz compared to triplet tunable marker of complex information processing and conscious states, with potential to complement or supplant conventional EEG in monitoring cognition and life-sign detection using advanced version of EEG, namely dodecanogram, DDG.