This chapter explores the intersection of transport, tourism, and health policymaking through the lens of Urbanimmunology, a framework that applies principles from the immune system to enhance urban and regional systems. It examines AI-driven traffic safety strategies that mimic immune responses to optimize traffic flow. The chapter also investigates the integration of transport and energy systems, focusing on the green transformation of heavy trucks through electric road infrastructure. By rethinking traditional transport and tourism policies, it introduces innovative approaches to align these sectors while promoting public health. Building on these insights, the chapter highlights the potential for integrating transport, tourism, and health policies to create resilient urban and regional environments, where each sector reinforces the others, fostering sustainable and healthy cities and regions. Urbanimmunology’s interdisciplinary perspective offers fresh approaches to addressing today’s complex urban and regional challenges.