Ulva species, a marine macroalgae commonly referred to as sea lettuce, has versatile application, rapid growth, and nutrient absorption efficiency, which has made it a promising candidate in the circular bioeconomy and advancement of the blue economy. This review integrates the current aspects of biochemical composition, bioactive compounds, and nutrient uptake of the species relevant to growth dynamics. Cultivation technologies have advancement in offshore techniques, land-based systems, and integration with aquaculture. The post-harvest technology is investigated, focusing on systematic harvesting, preservation, and biomass standardization implementation. The core concept of this study is Ulva potential in bioremediationBioremediation from wastewaterWastewater steams, particularly its ability to integrated nitrogen, phosphorus, and trace elements. Technological advancement for the optimization productivity and resource development such as bioreactors and dynamic modelling tools. The conversion of recovered nutrients into value-added products including functional food ingredients, bio-fertilizers, animal products, and industrial bio-products is reviewed, exhibiting Ulva’s role in sustainableSustainable product development. Life cycle assessment and feasibility studies for environmental and economic assessment for the sustainability and scalability of Ulva cultivation and processing. The review also highlights the regulations and policies for responsible Ulva farming and nutrient processing. Concluded with future perspectives, the study identifies the technological gap and research needs, developing an implementation plan to incorporate Ulva into global market with nutrient management with sustainable development frameworks.