Livestock husbandry represents a significant agricultural domain for numerous nations; however, it generates substantial quantities of organic waste that necessitate appropriate management, disposal, and valorization. Among the various livestock production methodologies, complaints regarding odour have been frequently recognized as a predominant environmental issue within the swine industry, surpassing challenges faced by other livestock production systems. As reported by the Department of Agriculture, Forestry and Fisheries, swine production constitutes a vital economic sector in South Africa, playing a considerable role within the country’s agricultural landscape by contributing approximately 2.15% to the primary agricultural sector. On a global scale, China is at the forefront of swine production, followed closely by the European Union and the United States, with Asia representing the largest proportion of the worldwide swine population. In the year 2023, China achieved a production level exceeding 55 million metric tons of swine. The swiftly expanding porcine husbandry sector produces effluents of considerable strength, characterized by the presence of organic constituents, ammonia, phosphates, malodorous gases, suspended particulates, and pathogenic organisms. The treatment of swine effluent and the management of odours constitute critical elements in the pursuit of sustainable animal husbandry; consequently, more stringent regulations pertaining to the livestock sector that mandate both efficient treatment and odour mitigation are being enacted. The process of wastewater treatment encompasses various methodologies aimed at the elimination of contaminants and the safe reintegration of treated water into the hydrological cycle. A range of physical, chemical, and biological treatment techniques have been innovated and implemented. The implementation of appropriate treatment methodologies for various sources of livestock wastewater can be proficiently transformed via bioprocessing strategies into valuable resources, including energy, fertilizers, bioplastics, and animal feed. This may encompass procedures such as anaerobic digestion for biogas generation, the treatment and subsequent reuse of water, and the synthesis of nutrient-dense solid and liquid fertilizers. The objective of valorization is to diminish the ecological ramifications of waste while simultaneously fostering a more sustainable and efficient system for livestock production. This chapter will concentrate on various microbial methodologies, encompassing aerobic activated sludge systems and anaerobic treatment processes, which have been previously employed for the management of swine waste. A significant limitation of these methodologies is the generation of a range of deleterious and toxic by-products, including sulphide, nitrite, and nitrogen oxides. Consequently, the inquiry emerges as to whether viable alternative strategies for alleviating malodourous emissions in the treatment of swine waste can be effectively implemented.